When used correctly, natural health supplements can provide a variety of benefits. They can support overall health, help address specific nutrient deficiencies, and may assist in managing certain health conditions. These supplements can help fill nutritional gaps, enhance immunity, increase energy levels, and potentially reduce the risk of chronic diseases by supplying antioxidants.
Important Considerations When Using Natural Health Supplements
Consult with a Healthcare Professional: It is essential to speak with a doctor or registered dietitian before starting any new supplement regimen, especially if you have pre-existing health conditions or are taking medications.
Not a Replacement for a Healthy Diet: Supplements should not be considered a substitute for a balanced diet that includes a variety of fruits, vegetables, and whole foods.
Potential Risks and Side Effects: Although natural supplements are generally regarded as safe, they can still cause side effects in some individuals. It is important to be aware of potential risks and monitor your body’s response to any new supplement.
Are you an athlete looking to perform at your best in your next event? Whether you want to achieve faster times, cover longer distances, score more goals, or recover quickly afterward, the answer is likely “yes.” Remember, enjoyment and performance in sports are closely linked.
Whether you’re an elite Ironman competitor or a casual exerciser, your immune system is crucial to your athletic performance. It not only helps prevent illness but also affects your overall ability to perform effectively.
Extreme Athletes
Extreme athletes understand the intense demands of training, sleep, performance, and recovery. The lead-up to an event can cause mental stress, draining energy and negatively impacting sleep quality, which in turn affects performance. Post-event recovery takes time, and you may be more vulnerable to illness for about five days.
Enthusiastic Athletes
As an enthusiastic athlete, your experience may differ from others. Moderate exercise boosts your immune system, but there’s always room for further improvement in performance.
The difference between extreme and enthusiastic athletes is summarized
Bente Klarlund Pedersen and Anders Dyhr Toft from the Copenhagen Muscle Research Centre and the Department of Infectious Diseases explain the difference between extreme and enthusiastic athletes.
They state, “Moderate exercise across the lifespan seems to increase resistance to upper respiratory tract infections, whereas repeated strenuous exercise suppresses immune function.”*
The key to supporting extreme and enthusiastic athletes is to strengthen and enhance the immune system.
To begin with, let’s cover some basics. Your immune system is composed of immune cells and immune proteins (technically known as cytokines). Immune cells include macrophages, often referred to as “big eaters.” These cells play a crucial role in protecting us by consuming viruses, fungi, and bacteria.
Immune proteins serve as the regulators of the immune system, directing its actions. They function most effectively when they are balanced; any imbalance can lead to issues.
Additionally, immune proteins connect the immune system to the central nervous system. They help to facilitate the release of regulating hormones, which can impact various everyday performance issues.
Importantly, immune proteins can be increased and balanced, contributing to overall health and performance.
Balancing immune proteins is an effective way to enhance the immune system’s strength.
A diet alone may not provide the necessary immune proteins for this balance. This is where Glutrasol comes in. This performance supplement enhances immune protein balance in two key ways.
First, balanced cytokines are injected directly into the digestive tract, where they remain stable before being absorbed through the intestinal wall. Second, the body produces even more balanced cytokines, which help replace any missing immune proteins. See:
By using specialized nutraceuticals, you can enhance your athletic performance.
All athletes can experience significant improvements as immune protein balance is restored, leading to increased energy levels and an overall sense of well-being. Stamina replaces mere endurance, and motivation comes easily when you feel good.
For extreme athletes, recovery is swift, and the risk of respiratory infections is reduced.
Enjoy reaching your new athletic potential! The choice of whether to share this with your competitive friends is up to you!
As patients explore personalized treatment options, healthcare providers should do the same.
Healthcare treatment is rapidly evolving. Increasing numbers of consumers are showing interest in an approach known as “integrative medicine.” This approach offers new possibilities for enhanced and personalized patient care.
Integrative medicine is not entirely new; its principles are straightforward and sensible. Rather than relying solely on a one-dimensional approach, such as simply “taking this pill three times a day,” integrative medicine suggests that the best healthcare solutions may involve a combination of medications and complementary remedies. These can include a balanced diet, regular exercise, vitamins, and FDA-approved specialty nutraceuticals.
What are specialty nutraceuticals, or medical foods?
Specialty nutraceuticals are dietary products specifically designed to support particular bodily structures or functions. The term broadly refers to any product derived from food sources that provides additional health benefits beyond the basic nutritional value found in foods.
While terms like “exercise” and “vitamins” are commonly understood, “specialty nutraceutical” may be unfamiliar to many in the healthcare field. It’s essential to note that nutraceuticals are not substitutes for traditional drugs or medical treatments; instead, they are part of an integrative approach to support health issues safely and effectively.
What is the difference between a nutraceutical and a medicine?
Pharmaceuticals are FDA-approved drugs specifically designed to treat diseases and provide immediate relief. In contrast, nutraceuticals are nutrient-rich dietary substances derived from whole foods or parts of food sources that offer health benefits beyond basic nutrition.
Doctors and pharmaceutical companies are slow to adapt to specialty nutraceuticals.
Although consumer interest in specialty nutraceuticals is on the rise, many doctors and pharmaceutical companies remain hesitant to embrace them. A recent survey by the American Hospital Association found that 44% of respondents identified “physician resistance” as one of the top three barriers to adopting integrative medicine programs that may include specialty nutraceuticals.
Additionally, some pharmaceutical companies view these supplements not as an opportunity to serve their customers and explore a new revenue stream, but rather as a threat to their existing businesses. This resistance from the pharmaceutical sector is unfortunate, as specialty nutraceuticals offer promising new options for both doctors and patients, as well as a significant market opportunity for these companies.
Although the process may be slow, the specialty nutraceutical market is expected to grow in the coming years, offering patients more solutions and treatment options.
Nutraceuticals occupy a space between food and pharmaceuticals.
They include foods and substances, or combinations of substances, made up of natural molecules or elements. Nutraceuticals are used to maintain or improve health, as well as to treat or prevent diseases and conditions.
To benefit consumers, pharmaceutical companies can take the following steps:
Recognize the increasing consumer interest in personalized treatments and advocate for these options.
Consider specialty nutraceuticals as valuable additions to their product lines, providing a clear competitive advantage.
License patented specialty supplements that are already FDA-approved for manufacturing and distribution in their core markets. Since these products are FDA-approved, research and development costs are minimal, and the time to market is significantly reduced.
Produce and offer products with substantial profit margins.
Assist physicians and clinics in refining their treatment protocols, enabling them to differentiate themselves more effectively in the market.
Medical Foods: The concept of personalized treatment has become increasingly relevant.
Medical foods play a crucial role in this emerging standard and perspective. This new approach presents a unique opportunity for large pharmaceutical companies to connect with customers and enhance their profits. Meeting the rising consumer demand aligns with the interests of doctors who wish to provide more options for their patients, as well as pharmaceutical companies looking to strengthen their competitive advantage.
Transfer Factor: This is a chemical derived from humans or animals that have already developed immunity against a specific disease.
Glucans: Glucans are polysaccharides made from D-glucose and are linked by glycosidic bonds. They are categorized into two forms: alpha-glucans and beta-glucans.
Lactic Acid-Generating Bacteria: This group includes Gram-positive, non-respiring, non-spore-forming bacteria, either cocci or rods, that produce lactic acid as the primary byproduct of carbohydrate fermentation.
This disclosure focuses on the biochemistry of Transfer Factor.
The effectiveness of Glutrasol and Transfer Factor Ultra is demonstrated by test groups that consistently show significant improvements compared to control groups.
Here is information on how (biochemically) they work.
II. Inducer/Suppressor Fraction of Transfer Factor
T-lymphocytes produce transfer factors and can transfer the ability to recognize a pathogen to cells that have not been previously exposed to the pathogen. They also heighten the immune system’s ability to react (increased reactivity or inducer function) to pathogens. Transfer factor produces a trigger for T-cell recognition of an antigen.
The transfer factor is a mixture of peptides, typically with a molecular weight < 10,000 Daltons. It’s more appropriate to speak of “transfer factors” instead of “transfer factor.” Fortunately, today’s preparative methods produce consistent mixtures, resulting in repeatable responses.
Fractions within the mixture serve different (and sometimes opposite) purposes. Two significant fractions are (1) the inducer fraction and (2) the suppressor fraction [1][2]. Opposing functions were confirmed using the direct Leucocyte Migration Inhibition (LMI) test.
These two fractions are consistent with field observations that the transfer factor balances the immune system.
For example:
The inducer fraction of transfer factor biochemistry links the immune cells with an antigen-binding site, thereby increasing their reactivity to an antigenic stimulus. This is advantageous when a higher immune response is required. CortControl’s enhanced vaccine response arises from an inducer fraction. Several researchers have documented the inducer effects of transfer factors [3][4][5].
The suppressor fraction blocks the response of the T-cells and signals a down-regulation of the immune response. This is helpful in allergic or autoimmune conditions. Animal studies demonstrate improvement in cases where the immune system is overactive. This arises from the suppressor fraction. Cortesini R. et al. [6] showed that CD8+CD28-Ts represent a unique subset of regulatory cells within the transfer factor that initiates a suppressive loop. Filaci [7] supported Cortesini’s work and related autoimmune diseases to the absence of CD8+ suppressor T lymphocytes. Filaci further found that “CD8+ Ts can be generated in vitro from CD8+CD28-T lymphocytes. A key role in their generation is played by monocytes that secrete interleukin-10 (IL-10) after granulocyte macrophage-colony-stimulating factor (GM-CSF) stimulation.”
Aleli Salazar-Ramiro et al. [8] view cancer as an autoimmune disease and propose a transfer factor for cancer therapy. This is supported by CortControl’s veterinary work on horses, dogs, and cows [9], where cancer symptoms were visibly reversed.
III. TH1/TH2 Helper Cells and Cytokines
Reviewing the helper lymphocyte paradigm helps categorize the applications of transfer factor. Helper lymphocytes develop along two cell populations: TH1 and TH2. Transfer factors from both lymphocyte lines are represented in the transfer factor biochemistry. TH1 and TH2 cells perform distinct functions and produce distinct cytokines, proteins that serve as messenger molecules.
Cell-mediated or TH1 helper responses are crucial to the body’s ability to defend itself against viruses, fungi, parasites, cancer, and other intracellular organisms. TH1 cells modulate cell-mediated immunity.
Cytokines are functionally similar to hormones but are not associated with a specific gland.
They appear to operate as keys and templates.
Cytokines are a broad and loose category of small proteins essential in cell signaling. Due to their size, cytokines cannot cross the lipid bilayer of cells to enter the cytoplasm; therefore, they typically exert their functions by interacting with specific cytokine receptors on the target cell surface.
Stereochemistry is important.
What is stereochemistry in simple terms?
A branch of chemistry that deals with the spatial arrangement of atoms and groups in molecules.
The spatial arrangement of atoms and groups in a compound and its relation to the properties of the compound.
The attachment of a cytokine to an immune cell receptor starts a specific immune signal within the target cell. Signals translate into direct action, increase the production of antibodies against an invading virus, or initiate the production of other cytokines to propagate the signal.
IV. TH1/TH2 Predominant Phenotypes
One aspect of immune regulation involves homeostasis between T-helper 1 (Th1) and T-helper 2 (Th2) activity [10]. TH1/TH2 balance correlates with good health, and over-activation in either direction sets the stage for disease.
Th1 and Th2 helper cells direct different immune response pathways and produce different cytokines. Either pathway can downregulate the other.
Steven Bock, MD, correlated disease conditions to an imbalance of TH1 and TH2. For example, if one has a TH2-dominated condition, the disease conditions that tend to prevail are:
Allergies
Chronic sinusitis
Atopic eczema
Asthma
Systemic autoimmune conditions such as lupus erythematosus and mercury-induced autoimmunity
Vaccination-induced state
Certain cases of autism
Hyperinsulinism
Pertussis vaccination
Malaria
Helminth infection
Hepatitis C
Chronic giardiasis
Hypercortisolism
Chronic candidiasis
Cancer
Viral infections
Ulcerative colitis
If one has a TH1-dominated condition, the conditions that tend to prevail are:
Diabetes type 1
Multiple sclerosis
Rheumatoid arthritis
Uveitis
Crohn’s disease
Hashimoto’s disease
Sjögren’s syndrome
Psoriasis
Sarcoidosis
Chronic Lyme disease
H. pylori infections
E. histolytica
Glutrasol field observations show successes in both categories. For example, international travelers avoid flu and colds by consuming Glutrasol before a trip. In addition, Ramaekers Nutrition has success with psoriasis, Crohn’s disease, and H pylori infections (among a 20-year list of others). The biochemistry of transfer factor in Glutrasol contains cytokines from both TH1 and TH2 cells. It produces different cytokines in response to various situations.
Alvarez-Thull L, Kirkpatrick CH [11] note that “Transfer factor treatment selectively affects cytokine production in response to antigenic stimulation.”
Fabre RA et al. [12] (in a pulmonary tuberculosis study) showed that “the treatment with murine or human TF [transfer factor] restored the expression of TH-1 cytokines, TNFalpha and iNOS, provoking inhibition of bacterial proliferation and significant increase of DTH and survival.”
V. Adjusting to Change
Malaria is cited as a TH2-dominated condition. WHO [13] and PATH are working on a robust malaria vaccine.
CortControl acknowledges that parasites can mutate [14] and present a changing appearance to the immune system. This is one reason why malaria victims experience cyclical flare-ups. Antibody vaccines are specific and not designed to keep pace with mutations.
Maturation time for TH1 or TH2 cells is 10-14 days. In contrast, the biochemistry of transfer factor works on the innate immune system and responds within 24-48 hours. Transfer factor empowers the immune system to stay current with mutations.
CortControl predicts that the immediate benefits of combining Glutrasol with the malaria vaccine will be:
Increasing vaccine efficiency and
Minimizing relapse or re-infection.
VI. Rebalancing TH1 and TH2 Levels
Transfer factor can change TH1/TH2 predominance conditions within 48 hours [15].
This observation asks, “How can Transfer Factor change a predominantly TH-2 Immune System to a predominant TH-1 System so rapidly?”*
*The hypothesis of new TH1 cells was dismissed early because it takes 10-14 days to mature new TH1 cells.
The answer is “conversion by eomesodermin,” which was studied in 2003 [16].
Eomesodermin. Also known as T-box brain protein 2, it is a protein encoded by the EOMES gene in humans. The Eomesodermin/Tbr2 gene, EOMES, encodes a member of a conserved protein family that shares a common DNA-binding domain, the T-box.
In that study, already differentiated TH2 cells were converted into TH1 cells. Eomesodermin is a T-box transcription factor related to T-bet and is already characterized as a key regulator of mesodermal differentiation. Eomesodermin was up-regulated explicitly in activated CD8+ cells [one of the transfer factor’s actions].
The conversion of TH2 cells to TH1 cells is particularly relevant to viral vaccines and malaria, which tend to be TH2-dominated immune responses. In the opposite direction, the conversion of TH1 to TH2 is advantageous for Conditions Such as Rheumatoid arthritis or Crohn’s disease.
VII. Viruses, Bacteria, and Parasites
Web MD notes, “Transfer factors are used for infectious conditions in people with weak immune systems. These infectious conditions include bacteria or viruses in the bloodstream (septicemia), sinus infections, bronchitis, influenza, swine flu, the common cold, shingles, chickenpox, hepatitis B, fungal infections such as coccidioidomycosis, yeast infections (candidiasis), parasitic infections such as leishmaniasis and cryptosporidiosis, and leprosy.
Transfer factors are also used against infections caused by viruses such as cytomegalovirus (CMV) and Epstein-Barr virus, bacteria such as Mycobacterium tuberculosis, Mycobacterium fortuitum, and Mycobacterium avium, and yeast-like fungi such as Cryptococcus and Pneumocystis carinii.
The Glutrasol formulation dramatically lowered the mortality rate of parasite-infected livestock herds [9]. Simultaneously, weight gain improved.
CortControl does not believe that we “cured” the affected herds. Instead, we believe Glutrasol better staged the subject’s immune system to resist parasites and opportunistic infections.
This immune response has applications for countries where water-borne parasites negatively affect child development.
Stunted childhood growth is a significant global health issue. Low weight gain in livestock and stunted human growth are probably related.
VIII. Staging the Immune System
The response to vaccination depends on the recipient’s health. Vaccines work best for healthy people. Conversely, a person with a weakened immune system may not derive the full benefits from the calculated vaccine. This relationship is significant in less developed countries, where unsanitary conditions impact overall health.
Dr Mandal [17] notes, “This [a lower-than-expected vaccine response] could be due to various reasons. Sometimes, this is because the host’s immune system doesn’t respond adequately or at all. This could be in diseased persons with lowered immunity, e.g., in people with diabetes, those on steroids or other immunity-suppressing drugs, or those with HIV infection.
The non-development of immunity to disease could also be due to the host’s immune system not having a B cell capable of generating antibodies against the antigen or microbe, or the immune system may not be strong enough to fight off the infection.
Glutrasol. Formulated to narrow the health gap and make vaccine benefits accessible to a larger population.
IX. Adjuvant Application
Several articles suggest the use of the Transfer Factor as an adjuvant.
An adjuvant is a chemical substance added to some vaccines to help the body’s immune system respond more effectively to the vaccine’s antigens.
Schroder et al. [18] state, “This interspecies adjuvant effect was proportional to the dose of the ‘transfer-factor’ preparations administered, depended on the method of their preparation, and was expressed in the administration of the preparations simultaneously with the immunization.”
Wang et al. [19] state, “In conclusion, these results suggest that TF [transfer factor] possess better cellular immune-enhancing capability and would be exploited into an effective immune-adjuvant for inactivated vaccines.”
X. Dramatic Pictures of Results of Consuming Transfer Factor
The following images are two patient examples. We have an extensive database of animal results using our patented formulas.
Mazaheri R, Hamblin AS, Zuckerman AJ., “Cell-mediated immunity: correlation of mixed-leucocyte-macrophage migration inhibition with delayed-type hypersensitivity after immunization and donor-specific transfer of cell migration inhibition by dialyzable leucocyte extract,” Cell Immunol. 1983 Nov;82(1):147-62. https://www.ncbi.nlm.nih.gov/pubmed/6196129
Kirkpatrick CH, Rich RR, Smith TK., “Effect of transfer factor on lymphocyte function in anergic patients,” J Clin Invest, 1972 Nov;51(11):2948-58. https://www.ncbi.nlm.nih.gov/pubmed/5080419
Salazar-Ramiro A, Hernández-Pedro NY, Rangel-Lopez E, Cruz VPD, Estrada-Parra S, et al., “Dialyzable Leukocyte Extract (Transfer Factor) as Adjuvant Immunotherapy in the Treatment of Cancer,” MOJ Auto Dis 1(1): 00003. DOI: 10.15406/mojad.2016.01.00003.
Cortesini R1, LeMaoult J, Ciubotariu R, Cortesini NS., “CD8+CD28- T suppressor cells and the induction of antigen-specific, antigen-presenting cell-mediated suppression of Th reactivity”, Immunol Rev. 2001 Aug;182:201-6. https://www.ncbi.nlm.nih.gov/pubmed/11722635
Filaci G. et al., “Nonantigen specific CD8+ T suppressor lymphocytes originate from CD8+CD28- T cells and inhibit both T-cell proliferation and CTL function”, Hum Immunol. 2004 Feb;65(2):142-56. https://www.ncbi.nlm.nih.gov/pubmed/14969769
Salazar-Ramiro A, Hernández-Pedro NY, Rangel-Lopez E, Cruz VPD, Estrada-Parra S, et al., “Dialyzable Leukocyte Extract (Transfer Factor) as Adjuvant Immunotherapy in the Treatment of Cancer,” MOJ Auto Dis 1(1): 00003. DOI: 10.15406/mojad.2016.01.00003. http://medcraveonline.com/MOJAD/MOJAD-01-00003.php
Kidd P., “Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease”, Altern Med Rev. 2003 Aug; 8(3):223-46. https://www.ncbi.nlm.nih.gov/pubmed/12946237
Kirkpatrick CH, Rich RR, Smith TK., “Effect of transfer factor on lymphocyte function in anergic patients,” J Clin Invest, 1972 Nov;51(11):2948-58. https://www.ncbi.nlm.nih.gov/pubmed/5080419
To improve overall health and integrated treatment efficacy, Glutrasol supports the immune system by employing three chemistries key to Glutrasol‘s science-based specialty supplement: transfer factor, beta-glucans, and lactic acid-generating bacteria.
Transfer Factor
Transfer factor is commonly derived from colostrum, a cow’s first milk after calf delivery. This milk contains information in the form of small proteins (polypeptides) that transfer immunity from cow to calf or from cow to human.
In Glutrasol, the proteins are separated by molecular weight. Other sources of transfer factors include eggs, sheep, goats, and lysed cells. As various sources are mixed, the scope of immunity typically increases. If people take transfer factors daily, their immune capability—as measured by killer white blood cells—could increase by as much as 250%.
Proteins are separated by molecular weight.
Beta-Glucan
Beta-glucan stimulates the two principal parts of the body’s immune system: the innate and the acquired immune systems.
Innate immune systems
In the innate immune system, beta-glucan binds to macrophages, a type of white blood cell that detects bacteria, viruses, and other pathogens, thereby coordinating the body’s defenses against them. When activated by beta-glucan, macrophages have a greater ability to identify and destroy foreign intruders. After devouring pathogens through phagocytosis, macrophages communicate the presence of the intruder to the body’s other defenders. Research shows that macrophages fortified by beta-glucan can rally the body’s defenses.
Macrophage activation via the cell surface receptor.
Acquired immune systems
After this, the acquired immune system joins the fight. With the information transmitted from the macrophages, the acquired immune system learns to manufacture other killer cells and blood factors designed to defend against a specific attack. These include B-cells, which produce antibodies. The antibodies, working in conjunction with the innate immune system, bind to and destroy foreign invaders, forming clusters. Macrophages then overwhelm these. This process is how the body eliminates infections and diseases.
Lactic Acid-Generating Bacteria.
Lactic Acid-Generating Bacteria
Many assume that glucose is the primary energy source for living tissues; however, there are indications that neurons in the human brain preferentially metabolize lactate rather than glucose.
Digestive Health
Lactic acid-generating bacteria also have significant positive effects on digestive health. Foods such as cod liver oil and sauerkraut, for example, derive their benefit from lactic acid-generating bacteria. The liver, pancreas, and kidneys are less stressed when digestion is good.
The immune system is supported because beneficial lactic acid-generating bacteria displace pathogens in the digestive tract, restoring healthy mucus in the intestinal lining.
Supporting Immune Health
—Richard Bennet, Ph.D.
The Science Behind Glutrasol: An Integrative Approach to Supporting Immune Health
The global need to address immunodeficiency disorders is real and immediate. Richard Bennet, Ph.D., states, “Our ability to create a really healthy immune system represents the greatest potential gains in health in the world.”
Immune System Health
The outcomes resulting from diminished immune system health are numerous and varied. Compromised immune health affects the ability to fight off pathogens, leaving at-risk populations, especially the elderly or those in developing countries, at a disadvantage in avoiding disease.
At-Risk Populations
Seniors
Many seniors are at risk of contracting disease due to physical limitations, existing health concerns, or nutritional deficits. Providing a robust immune health foundation can effectively arm seniors with a better ability to maintain good health and vitality.
Developing Countries
In many developing countries, vast numbers of at-risk populations arrive at support organizations with immune systems that are severely compromised, either from inadequate nutrition, poor sanitation, environmental stress, or aging. Poor sanitation, nutritional food, and environmental distress are common and systemically complex to overcome.
One solution to support these at-risk groups is to provide nutraceuticals or specialty supplements, such as Glutrasol, to help these populations improve their immune system health.
Developing countries are located mainly in Africa, Asia, Latin America, and the Middle East.
Infectious disease epidemics cost the world US$60 billion each year. They match wars and natural disasters in their capacity to endanger lives, disrupt societies, and damage economies.
— Coalition for Epidemic Preparedness Innovations (CEPI)
The Science Behind Glutrasol: Immune-System Health and Antigen Exposure
Immune system health is an important factor in fighting disease
Fighting Disease
Immune system health is a crucial factor in combating disease. Dr. Ananya Mandal, MD, notes that “the reason for non-development of immunity to a disease could also be that the host’s immune system does not have a B cell capable of generating antibodies against the antigen or microbe, or the immune system may not be strong enough to fight off the infection.”
Kenneth L. Marcella, DVM, states, “It is the immune system, after all, which allows humans and animals to recognize and remember potentially harmful foreign substances such as bacteria and viruses. The immune system allows us to respond to these threatening invaders in our systems.”
CortControl’s Glutrasol helps build the immune system to respond better to antigenic exposure.
Maximizing Immunity and Extended Protection
Glutrasol is a nutraceutical specifically developed to support immune system health. When Glutrasol compounds were tested on cattle, cell-mediated immunity increased 4-5 times. Additionally, non-responsive populations to an antigenic stimulus without Glutrasol compounds developed a response when treated with Glutrasol compounds. Furthermore, animal testing demonstrated increased protection periods, rendering recipients less susceptible to additional health concerns.
Global healthcare workers care for vast populations in many developing countries.
Efficacy and extended protection periods affect logistics and economics. From a practical standpoint, reducing the frequency of interactions stretches the budget.
Fewer visits are required to achieve goals.
Delivery costs drop proportionately.
More time per visit becomes practical.
The need for follow-up treatments decreases.
Effective Delivery is Critical
“We should anticipate a growing frequency of infectious disease threats to global security,” says Peter Sands, Chair of the Commission on a Global Health Risk Framework for the Future. Maximizing the health of those in developing countries can help minimize the impacts of each new pandemic.
Treatments
Treatments must be stable and easy to manage in extreme climates and areas with significant sanitation challenges. Doses must be small, lightweight, and easy to administer and distribute.
Researchers
Researchers are looking at ways to enhance immune system health with easy-to-administer integrative solutions. Easy-to-transport specialty supplements are a promising approach. Glutrasol provides such a solution.
How Does Glutrasol Help Support Immune Health?
Glutrasol’s research shows:
An increased antibody titer for a subject by 4-5 times
Extended protection between vaccine booster treatments
Improved response to an antigenic stimulus
Provides ease of delivery in hard-to-reach populations
The product is stable in scorching climates
Additional positive, proven outcomes from animal research
Reduced stress
Increased food utilization or growth rate
Improved offspring mortality
Increased fertility
Supporting Fertility
The Science Behind Glutrasol: An Integrative Approach to Supporting Fertility
Many people consider the prospect of having children one of life’s great experiences. Sadly, though, according to the Mayo Clinic, between 10% and 15% of all couples of childbearing age have difficulty either conceiving or carrying a pregnancy to term. The health of both men and women contributes to this statistic.
Immunity vs. Fertility
Contributors to fertility support are numerous. Among these are a healthy immune system and balanced levels of cytokines.
The immune system and reproductive systems are interdependent. Reproductive immunology is a well-established field of medicine that studies interactions (or their absence) between the immune system and components related to the reproductive system.
Cytokines are critical components of the immune system.
They are small proteins that act as immunomodulatory agents, impacting the immune response. The body’s immune resources are naturally prioritized to address health threats first. As a lesser priority, fertility capacity is negatively affected when the body fails to fight pathogens, even at subclinical levels.
Dr. Marie-Pierre Piccinni, from the Institute of Internal Medicine and Immunallergology at the University of Florence, Italy, found that cytokine balance plays a crucial role in implantation and successful pregnancy (Piccinni et al., 1998). Cytokine balances further allow the survival of the fetus throughout gestation. (Piccinni and Romagnani, 1996).
Further, a clinical study performed on 100 healthy women showed that a low FAAH (fatty acid amide hydrolase) activity in lymphocytes correlated with spontaneous abortion. [Source: Mauro Maccarrone, Department of Experimental Medicine and Biochemical Sciences and † Division of Obstetrics and Gynecology, University of Rome Tor Vergata, Rome, Italy; and ‡ Fatebenefratelli Association for Research, San Giovanni Calibita Hospital, Rome, Italy]
The Science Behind Glutrasol: Fertility and Cytokine Balance
There are inflammatory and non-inflammatory cytokines
Women’s Fertility
The inflammatory-to-noninflammatory cytokine ratio is a known reliable indicator of women’s fertility. If the ratio is too high, conception is unlikely to occur. If the conception probability is more balanced, it is higher. Pathogens interact with the immune system to induce the production of inflammatory cytokines. In contrast, friendly bacteria (such as lactic acid bacteria) create non-inflammatory cytokines.
Inflammatory Immune Cells
Inflammatory immune cells are specifically drawn to the site of a viral infection. Once there, they produce their characteristic inflammatory cytokines. A robust immune system would soon rid the body of the virus, and the level of inflammatory cytokines would fall. A weak immune system won’t finish the job, and high inflammatory cytokines will persist, even though viral symptoms may not be obvious.
One crucial factor related to fertility is maintaining the proper balance of inflammatory and non-inflammatory cytokines.
Both Sexes Impacted
Cytokine balance can affect men and women differently.
A 2014 study published in the journal Seminars in Reproductive Medicine showed that inflammation can disrupt the balance of estrogen and progesterone, the two primary hormones involved in the menstrual cycle. When these two hormones are out of balance, it’s nearly impossible to get pregnant or carry a baby to full term.
Male fertility is also impacted. Anna Havrylyuk, Department of Clinical Immunology and Allergology, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine, has noted that “Cytokines have been important mediators of immunity, and can be involved in numerous processes in the male genital tract, including acting as immunomodulatory elements within the male gonad.”
Stress, Immune Function, and Fertility
Stress affects immune function, and in turn, immune function impacts fertility.
Allen Morgan, MD, the director of the Shore Institute for Reproductive Medicine, says, “When stress-reduction techniques are employed, something happens in some women that allows them to get pregnant when they couldn’t get pregnant before.”
And, as Margareta D. Pisarska, MD, the co-director of the Center for Reproductive Medicine at the Cedars Sinai Medical Center in Los Angeles, has observed: “It’s becoming more and more important, in terms of what studies we do, to focus our efforts on the physiological effects of stress and how they may play a role in conception.”
The connection between immune function and stress is evident. When your body is stressed due to illness or emotional distress, it fights to get well. Reproduction is a lesser priority. At the University of California in San Diego, researchers found that highly stressed women ovulated 20% fewer eggs than women who experienced lower stress.
How Does Glutrasol Help Support Fertility?
Glutrasol strengthens the immune system with three active components: transfer factor, beta-glucans, and lactic acid-generating bacteria to support fertility. The combination contains and balances cytokines. Strengthened immunity leads to better health, and better health supports fertility.
Glutrasol offers a personalized, all-natural alternative for enhancing fertility.
Glutrasol is a cost-effective fertility aid that is less costly, less invasive, and more effective than other claimed fertility aids. It can stand alone or augment an integrated program, providing a reliable and affordable solution. It offers a personalized, all-natural alternative for enhancing fertility.
Endurance athletes push through countless limits to compete in their sports. Most are rigorous and supremely disciplined regarding their nutrition, sleep, and training methods. However, many athletes may overlook immune system support as an integral component of their training, performance, and recovery regimen.
“When pursuing a more demanding training regimen, it’s important that the exerciser optimize immune responses,” writes Roy J. Shephard, M.D. Lond, PhD DPE, and Pang N. Shek, PhD, of the University of Toronto School of Physical and Health Education.
Optimal Performance
The power of immune support is often misunderstood. Our immune system is typically viewed as a matter of wellness versus illness, rather than optimal performance. But it’s fundamental to both and is found to be compromised in many endurance athletes.
In fact, in the British Journal of Sports Medicine, Bente Klarlund Pedersen and Anders Dyhr Toft, from The Copenhagen Muscle Research Centre and Department of Infectious Diseases, note that “Moderate exercise across the lifespan seems to increase resistance to upper respiratory tract infections, whereas repeated strenuous exercise suppresses immune function.”
How the Immune System Affects Athletic Performance
The immune system is directly connected to the central nervous system via immune-system proteins (technically called “cytokines”). These proteins facilitate the release of regulatory hormones, which mediate various physiological functions that occur on a daily basis. We’ll examine some of the impacts of immune system imbalance regarding their implications for training, performance, and recovery.
The Science Behind Glutrasol: Optimize Immune Responses
Demanding training regimens require a fast recovery
Before an Event
The value of a calm mind and sound sleep is well understood. Before an event, mental stress depletes energy reserves and reduces sleep quality.
Pre-event stress is cited as a negative factor in roughly 60% of competitors. Cortisol is the primary stress hormone. Mental stress effectively triggers the hypothalamus–pituitary–adrenal axis to produce cortisol. This sequence applies to all mammals.
Fortunately, the hypothalamic gland also houses the cortisol control loop. With the proper immune-protein stimulus from products like Glutrasol, cortisol production declines, sleep improves, and less vital energy is wasted.
During the Event
Changes in blood flow, increased cardiac output, heat dissipation, hydration status, and sweat production are critical factors during high-intensity exercise. These operating set points interact with each other and with the environment. Hormones (released in response to immune-protein permeation to the brain during exertion) affect the range of operation. Maintaining these factors within a normal range is crucial for optimal performance.
Shephard and Shek further suggest that “participation in a major marathon event increased the odds of infection almost sixfold relative to the experience of other runners who did not participate.”
Performance and Recovery
Electrolyte losses are controlled by hormonal thermal regulation. Imbalances among water, sodium, potassium, and chloride limit performance. Willpower can’t substitute for electrolyte imbalance.
Likewise, elevated cortisol and catecholamine hormone levels, which increase during moderate and strenuous exercise, can negatively impact performance. Supporting healthy cortisol levels by balancing cytokine proteins associated with the immune system can have a positive effect.
As Katsuhiko Suzuki, Faculty of Sport Sciences, Waseda University, noted, “Cytokines mediate exercise-induced inflammation, immunosuppression, and energy metabolism.” Glutrasol enhances cytokine balance to support peak performance and recovery.
Intense exercise stresses the body, and a fast recovery is necessary and a priority. We understand the importance of your recovery in maintaining peak performance.
“One of the major components of all training programs is the principle of progressive overload, implying working beyond a comfortable level,” write Joanna Ostapiuk-Karolczuk, Anna Kasperska, and Ryszard Botwina, of the University School of Physical Education, Poznan, Poland. “However, there is a fine line between improved performance and deterioration.”
Rebalance Faster
Without adequate recovery, an athlete is at risk of developing overtraining syndrome. Symptoms include respiratory infections, decreased serum testosterone, amenorrhea, impaired cognitive abilities, lack of concentration, and depression.
Recovery typically begins by replenishing electrolytes (such as sodium, potassium, and chloride) and water. At the finish line, everyone replenishes.
But that’s just the beginning. Recovery is primarily based on rebalancing the immune proteins, which in turn balance the body’s hormones and stabilize its homeostatic points. The body returns to its balanced condition, and Glutrasol enhances this balancing process, allowing you to rebalance faster and be less susceptible to illness or overtraining injuries.
Glutrasol is a reliable choice for recovery enhancement. It is 100% natural and contains no substances banned by the World Anti-Doping Agency (WADA). This natural composition reassures you that you’re fueling your body with the best without any concerns about doping.
Glutrasol testing has been conducted almost exclusively with animals at our parent company, Ramaekers Nutrition. For more than 50 years, veterinarians have prescribed many of the same compounds in Glutrasol to treat various diseases with considerable success.
Animal Testing
The animal testing range includes hundreds of thousands of cattle, pigs, horses, and other livestock, and the results have often been dramatic. Fertility in cattle, for example, has increased, in some cases, by more than 70%. In vaccine immuno-enhancement, antibody titers showed improvements of more than 360% at 21 days.
What is a Nutraceutical?
As a nutraceutical, Glutrasol is regulated by the FDA as a dietary supplement under the authority of the Federal Food, Drug, and Cosmetic Act. Unlike drugs, supplements are not intended to treat, diagnose, prevent, or cure diseases. A nutraceutical is a specialty supplement containing active constituents from foods, herbs, natural compounds, and other botanicals. Nutraceuticals offer pharmacological benefits and are specifically designed to support specific structural and functional applications in the body.
A team at Purdue University School of Veterinary Medicine conducted several studies to determine if vaccines can cause changes in the immune system of dogs.
Glutrasol$89.00
