Pemphigus Foliaceus


  • Natural Immunotherapy offers an effective therapy option for autoimmune conditions of the skin
  • Immune modulation is understood to balance the effects of cell-mediated and antibody-mediated immune system activity
  • Natural Immunotherapy is a safe, effective, and easy-to-administer therapy option

Patient: LadyBug

age/breed/sex: 10-month-old Quarter Horse Filly


LadyBug presented at 10 months old with signs of chronic illness, significantly retarded growth, and generalized unthriftiness. She was the size of a 5-month-old filly. Her prior veterinarian had diagnosed her with the autoimmune disease of pemphigus foliaceus via skin biopsy over her withers.

Internal medicine specialists state that 90% of horses diagnosed with pemphigus die or are euthanized within one year of diagnosis. Ladybug had visited Texas A&M Veterinary College. The therapies offered there were unsuccessful, and she was sent home with a very grave prognosis.

Pemphigus Foliaceus Therapy:

2/13/2002 - After consulting with Dr. Ramaekers, the owner started Transfer Factor Performance and Show without other steroids or immunosuppressive medications.

Pemphigus Foliaceus Follow up:

10/26/2002 - Ladybug significantly improved her clinical symptoms and physical condition within a few weeks. Lady is now normal-sized for her age and continues to grow and develop healthily.

Attending Veterinarian: Dr. Joe Ramaekers

Pemphigus Foliaceus. Horse is named Ladybug. This picture is before treatment.


Pemphigus Foliaceus. Horse is named Ladybug. This picture is after treatment.


Equine Transfer Factor Premix Pellets

Equine Transfer Factor Premix Pellets are available for horses of any age. These highly palatable supplement pellets are designed for your horse’s diet to support growth, performance, and disease challenges. The pellets contain patented immune therapy with transfer factor, mushrooms, and pre and probiotics.


Our Equine Transfer Factor Premix Pellets can be administered as a natural catalyst or as an effective substitute for traditional Western medicine approaches to therapy and prevention. For example, see Equine Results.

Transfer Factor Technology

Trust transfer factor technology to optimize immune system function. While many products use single rudimentary ingredients known to aid immune health, Ramaekers Nutrition delivers the only immune support products harnessing transfer factor supported by a unique, patented blend of essential nutrients and potent nutraceuticals. For example, see our Mission.

Patented Formulas

Our patented formulas use transfer factor technology. These formulas are derived from a proprietary blend of bioactive peptides and are based on the synergistic effect of combining naturally sourced biologically active peptides (transfer factor).

These bioactive peptides are extracted from bovine colostrum and egg yolks. To clarify, this blend combines unique plant-derived heteropolysaccharides, lactic acid-producing probiotics, and highly bioavailable micronutrients. To summarize, combining these immune active ingredients allows a dramatically enhanced immune response in equine health without side effects. For example, see Bovine ProductsCanine ProductsFeline ProductsEquine Products, and Other Livestock Products.

Unique Formulas

Our unique formulas help educate and boost the immune system for overall health and vitality. In short, immune education starts at birth and should continue throughout life with our patented products.

Ramaekers Nutrition’s products reflect a culmination of global research and clinical experience. Dr. Ramaekers is passionate about improving animal welfare. He is proud to be on the cutting edge of veterinary medicine (meet our veterinary team) and nutrition. Learn more about Ramaekers Nutrition.

Natural Pain Relievers

Dr. Ramaekers focused on replacing these nonsteroidal anti-inflammatories like Butazolodin and Banamine. To begin with, these pain relievers have many serious side effects, like bleeding ulcers. For example, see Equine Health.

With this in mind, he formulated products using natural pain relievers like curcumin, Boswellia, hyaluronic acid, glucosamine, and chondroitins. Most importantly, these natural products are equally effective and have no side effects.

Focusing on a mineral balance makes these products more available at the cellular level and allows joint absorption. Moreover, Dr. Ramaekers has replaced 80% of typical Western medicine pain relievers with his natural formulas.

Summary of Veterinarians’ Use of Ramaekers Immune Products in Equine Medicine

Clinical uses for the transfer factor products through immune enhancement and modulation are as follows:

Preventative Uses (pre and post-stress applications)

  • Shipping
  • Racing
  • Showing
  • Foaling
  • Weaning
  • Newborn
  • Surgery
These testimonials and case studies are presented for informational purposes only and are not intended as an endorsement of any product. The information is not intended to be a substitute for consulting your local veterinarian. Rather, they offer the reader information written by pet owners and/or veterinarians concerning animal health and products that have shown results.